Many people react to different foods without it is a food allergy. Histamine may play a role.

Histamine is a biogenic amine that is released in the body during allergic reactions, it also occurs in the venom of stinging nettles and insects as well as in different foods. Example concerns the effect the bronchi and gastrointestinal organs. Histamine is normally degraded in the intestinal mucosa by the enzyme diamine oxidase (DAO). Too little enzyme (DAO is inhibited or produces too little) or too much histamine (eg rotten fish) histamine is not sufficiently reduced, leading to reactions (eg, diarrhea).

Symptoms of histamine intolerance

The symptoms are less pronounced individually, as with most intolerance. One of the main symptoms include:

* Loose stool or diarrhea
* Low blood pressure
* High pulse rate
* Cardiac arrhythmias.

Laboratory diagnosis to clarify the histamine intolerance

In order to diagnose the exact cause of the symptoms, it is clearly necessary to determine the respective histamine, diamine oxidase and vitamin B6 levels in the blood. In previous studies it has been observed that people are supplied with a histamine intolerance poorly with vitamin B6. In connection with the histamine intolerance often occurs fructose intolerance. If there are several incompatibilities at the same time should also be excluded a chronic underlying disease.


nutritional Therapy

As part nutritional therapy, which aim to relieve the symptoms and prevent nutrient deficiencies, or to avoid it is first important to avoid foods containing histamine following:

* Ham,
* cheese,
* red wine,
* Yeast beer,
* marinated fish,
* sauerkraut,
* Sausage (especially salami),
* vinegar,
* spinach,
* tomato,
* Sparkling wine / champagne

Alcohol and histamine intolerance

The use of alcohol does not affect in any way adversely affect the well-being Histamine intolerance: Because alcohol

provides histamine in liquid form, which is rapidly absorbed by the body
Histamine inhibits DAO is not sufficiently reduced
increases the permeability of the intestinal wall: histamine enters the blood
acetaldehyde and encourage the body’s release of histamine.


Vitamin B6 is required for protein degradation. Rich in protein is eaten, the B6 is consumed and is not sufficient for histamine degradation available. It is also believed that vitamin C promotes the oxidative degradation of histamine. Must be taken on a regular intake of vitamin C and vitamin B6 to ensure the adequate supply of nutrients so. The following foods are good sources of vitamin B6:

Allergen-free cooking with histamine intolerance

Histamine is stable to heat and therefore will not be destroyed by the cooking and not by freezing. In food preparation should basically very fresh ingredients are used. Provided that the cold chain has been maintained, frozen products are in histamine. Canned or pickled vegetables lactic large amounts of histamine may be present.